The rooms of Holiday Inn Express Hotel & Suites San Diego Otay are large and beautifully appointed. The San Diego Holiday Inn Express Hotel in Otay Mesa welcomes you! This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from downtown San Diego and less than a mile from beautiful Tijuana, Mexico. Our new hotel in San Diego offers a convenient suburban location near the Cricket Wireless Amphitheatre, Knott's Soak City Water Park, Sea World, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Your family can learn about local history at the Cabrillo National Monument, the Air and Space Museum and the Maritime Museum. More...

Comfort Suites Otay Mesa is located on a quiet side street within walking distance to all the great restaurants, historical sites, and public transportation. The Comfort Suites Otay Mesa connects the maquiladoras of Tijuana, Mexico with the business community of Otay Mesa. Several Mexico and U.S. More...